ASCENT

Doctor in Snellville, GA

REVOLUTIONARY JOINT AND TEBDON REVIVAL

Get back to LIFE

DEHYDRATED

  • DEHYDRATED
  • AMNIOTIC FLUID DERIVED
  • BIOCHEMICALLY ACTIVE
  • INJECTABLE
Ascent is a dehydrated cell and cellular component (dCCC) injectable designed to protect, cushion, lubricate, and reduce inflammation by supplementing fluid environments within joints and tendons. Ascent is processed using the patent-pending Selectify™ process that retains key amniotic fluid cellular components and preserves the allograft in a shelf-stable format. The key benefits of Ascent are essential for tendon and joint relief:
  • PROTECTS AND CUSHIONS
  • LUBRICATES
  • REDUCES INFLAMMATION

Why amniotic fluid?

Amniotic fluid is a complex and dynamic bioactive substance that provides mechanical support to the fetus during gestation. It contains a wide variety of carbohydrates, proteins, peptides, lipids, pyruvate, electrolytes, enzymes and hormones that create the ideal environment that protects, lubricates, and cushions during the development of human anatomies.1 Using the patent-pending Selectify process, Ascent combines amniotic fluid’s unique set of cells and cellular components in a single injection.

Clinical Applications

Synovial Joints:
  • Ankles
  • Knees
  • Facets
Tendon Sheaths:
  • Tendons
  • Ligaments

Ascent™ should be maintained in its original packaging and stored at ambient temperature (0°C to 38°C) until ready for use. When stored properly in their original packaging, Ascent™ allografts are shelf-stable for up to three (3) years.

Cellular Components

In the body, cells communicate by detecting and responding to biochemical signals within their environment. Cellular components are biomolecules created by cells. These cellular components, including proteins like growth factors, act as signals within the body.2-3 More specifically, cellular components can help to support and supplement fluid environments like synovial joints, tendons, and wound exudate. Ascent does not incorporate viable cells; Ascent instead captures naturally occurring cellular signaling components in an injectable solution.

In the body, cells communicate by detecting and responding to biochemical signals within their environment. Cellular components are biomolecules created by cells. These cellular components, including proteins like growth factors, act as signals within the body.2-3 More specifically, cellular components can help to support and supplement fluid environments like synovial joints, tendons, and wound exudate. Ascent does not incorporate viable cells; Ascent instead captures naturally occurring cellular signaling components in an injectable solution.
Ascent is an injectable solution designed to cushion, protect, lubricate, and reduce inflammation by supplementing fluid environments within joints and tendons. It is made up of cells and cellular components retained from amniotic fluid. Amniotic fluid contains natural components, including proteins and growth factors, that protect the fetus as it grows and develops. Using a patent-pending method for processing amniotic fluid, Ascent captures these unique components in a single shelf-stable solution.
A range of factors including mechanical overloading, age, and genetics cause the body to degrade over time. These factors result in a complex series of biological events that cause inflammation and degeneration. In fluid environments within joints and tendons, this can cause cartilage breakdown, a change in synovial fluid composition, and microdisruptions. Ascent contains a unique array of natural biomolecular components, such as proteins, growth factors, cytokines, glycosaminoglycans, and enzymes, that counteract these changes by supplementing fluid environments to provide lubrication, cushioning, and protection, within joints, tendons and wound exudate.
The procedure for injecting Ascent is very similar to a simple steroid injection. It is quick, easy, and unlike many regenerative therapies, doesn’t require an invasive procedure. The injection site is cleaned, anesthetized and injected – all in less than 10 minutes.

Ascent is a product of StimLabs, LLC. StimLabs is dedicated to providing only the safest, highest quality products. Ascent is donated human tissue received from consenting full-term C-section mothers. All donors are individually evaluated by the StimLabs Quality Assurance Unit for eligibility. All donors are screened for communicable diseases, and a thorough medical history review is completed by the StimLabs Medical Director, a board-certified pathologist with over 20 years of experience in determining donor eligibility.

StimLabs is registered with the FDA as a tissue bank and meets or exceeds all applicable regulatory requirements for tissue banks. StimLabs has also met the rigorous accreditation requirements of the American Association of Tissue Banks (AATB), and is accredited for processing, release, storage, distribution and donor eligibility assessment of birth tissue. 

Component Comparison

 AscentSteroidHyaluronic AcidPRP
HA    
IL-1ra    
TIMPs    
Lactoferrin    
EGF, PDGF    
Shelf Stable, Single Injection    

Selectify is the proprietary method for processing Ascent. It begins with the selection of a variety of cell types called amniocytes. Once these desired cell types have been isolated, the remaining fluid is centrifuged to remove any undesirable components and purified using highly specialized filtration to retain a large group of key cellular components while also removing salts and other unnecessary molecules. The purified group of components includes proteins, growth factors, cytokines, and hyaluronic acid molecules that are beneficial for the reduction of inflammation and supplementation of nutrient deficient fluid environments.

The cells selected from the amniotic fluid during the first part of processing are recombined with the purified cellular components to create a concentrated solution that is preserved using lyophilization. The powder is then packaged and terminally sterilized.

MAKE AN APPOINTMENT